8KHN

Crystal structure of human methionine aminopeptidase 12 (MAP12) in complex with two cobalt ions

Summary for 8KHN

Entry DOI	10.2210/pdb8khn/pdb
Descriptor	Methionine aminopeptidase 1D, mitochondrial, COBALT (II) ION, TRIETHYLENE GLYCOL, ... (4 entities in total)
Functional Keywords	methionine aminopeptidase, metal-activated proteases, mitochondrial-targeted protein, hydrolase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	34652.66
Authors	Lee, Y.,Lee, E.,Hahn, H.,Kim, H.,Heo, Y.,Jang, D.M.,Kim, H.J.,Kim, H.S. (deposition date: 2023-08-22, release date: 2024-01-24)
Primary citation	Lee, Y.,Kim, H.,Lee, E.,Hahn, H.,Heo, Y.,Jang, D.M.,Kwak, K.,Kim, H.J.,Kim, H.S. Structural insights into N-terminal methionine cleavage by the human mitochondrial methionine aminopeptidase, MetAP1D. Sci Rep, 13:22326-22326, 2023 Cited by PubMed: 38102161 DOI: 10.1038/s41598-023-49332-6 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.51 Å)

Structure validation