8KDX

Tau-S214 Phosphorylation Inhibits Fyn Kinase Interaction and Increases the Decay Time of NMDAR-mediated Current

8KDX の概要

• エントリーDOI: 10.2210/pdb8kdx/pdb
• 分子名称: Tyrosine-protein kinase Fyn, Microtubule-associated protein tau (3 entities in total)
• 機能のキーワード: alzheimer's disease, fyn kinase, sh3 domain, tau protein and pxxp motif., peptide binding protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 8497.20

構造登録者

Padavattan, S.,Jos, S. (登録日: 2023-08-10, 公開日: 2024-02-28)

• 主引用文献: Jos, S.,Poulose, R.,Kambaru, A.,Gogoi, H.,Dalavaikodihalli Nanjaiah, N.,Padmanabhan, B.,Mehta, B.,Padavattan, S.; Tau-S214 Phosphorylation Inhibits Fyn Kinase Interaction and Increases the Decay Time of NMDAR-mediated Current.; J.Mol.Biol., 436:168445-168445, 2024; PubMed: 38218365; DOI: 10.1016/j.jmb.2024.168445

実験手法

X-RAY DIFFRACTION (1.01 Å)