8KCW

Cryo-EM structure of human SIDT1 bound to cholesterol

Summary for 8KCW

Entry DOI	10.2210/pdb8kcw/pdb
EMDB information	37112
Descriptor	SID1 transmembrane family member 1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	membrane protein
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	199475.83
Authors	Hirano, Y.,Ohto, U.,Shimizu, T. (deposition date: 2023-08-08, release date: 2024-06-12)
Primary citation	Hirano, Y.,Ohto, U.,Ichi, I.,Sato, R.,Miyake, K.,Shimizu, T. Cryo-EM analysis reveals human SID-1 transmembrane family member 1 dynamics underlying lipid hydrolytic activity. Commun Biol, 7:664-664, 2024 Cited by PubMed: 38811802 DOI: 10.1038/s42003-024-06346-8 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.77 Å)

Structure validation