8KBK

Structure of AcrIIA7 complexed with 1',2'-cADPR and cGG

Summary for 8KBK

• Entry DOI: 10.2210/pdb8kbk/pdb
• Descriptor: Inhibitor of Type II CRISPR-Cas system, (1S,3R,4R,6R,9S,11R,14R,15S,16R,18R)-4-(6-amino-9H-purin-9-yl)-9,11,15,16,18-pentahydroxy-2,5,8,10,12,17-hexaoxa-9lambda~5~,11lambda~5~-diphosphatricyclo[12.2.1.1~3,6~]octadecane-9,11-dione, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), ... (4 entities in total)
• Functional Keywords: viral protein
• Biological source: metagenome
• Total number of polymer chains: 4
• Total formula weight: 50530.71

Authors

Xiao, Y.,Feng, Y. (deposition date: 2023-08-04, release date: 2024-08-07)

• Primary citation: Xiao, Y.,Feng, Y.; Structure of AcrIIA7 complexed with 1',2'-cADPR and cGG; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.28 Å)