8K9Q

Cryo-EM structure of the GPI inositol-deacylase (PGAP1/Bst1) from Chaetomium thermophilum

8K9Q の概要

• エントリーDOI: 10.2210/pdb8k9q/pdb
• EMDBエントリー: 36995
• 分子名称: GPI inositol-deacylase,fused thermostable green fluorescent protein, CHOLESTEROL HEMISUCCINATE, (2~{S})-2-azanyl-3-[[(2~{R})-3-hexadecanoyloxy-2-[(~{Z})-octadec-9-enoyl]oxy-propoxy]-oxidanyl-phosphoryl]oxy-propanoic acid (3 entities in total)
• 機能のキーワード: bst1, glycosylphosphatidylinositol, gpi anchoring, gpi-ap, gpi-ap remodelase, integral membrane enzyme, lipase, lipid remodeling, membrane enzyme, membrane protein, nanodisc, pgap1, transmembrane enzyme, triad enzyme
• 由来する生物種: Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) (Thermochaetoides thermophila); 詳細
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 166137.28

構造登録者

Hong, J.,Li, T.,Qu, Q.,Li, D. (登録日: 2023-08-01, 公開日: 2023-12-20, 最終更新日: 2024-01-17)

• 主引用文献: Hong, J.,Li, T.,Chao, Y.,Xu, Y.,Zhu, Z.,Zhou, Z.,Gu, W.,Qu, Q.,Li, D.; Molecular basis of the inositol deacylase PGAP1 involved in quality control of GPI-AP biogenesis.; Nat Commun, 15:8-8, 2024; PubMed: 38167496; DOI: 10.1038/s41467-023-44568-2

実験手法

ELECTRON MICROSCOPY (2.84 Å)