8JWF

Cryo-EM structure of Plasmodium falciparum multidrug resistance protein 1 with H1 helix in complex with MFQ

Summary for 8JWF

• Entry DOI: 10.2210/pdb8jwf/pdb
• EMDB information: 36674 36679 36681
• Descriptor: Multidrug resistance protein 1, Mefloquine (2 entities in total)
• Functional Keywords: plasmodium falciparum, multidrug resistance protein 1, abc transporter, mfq complex, transport protein
• Biological source: Plasmodium falciparum (isolate 3D7)
• Total number of polymer chains: 1
• Total formula weight: 163143.12

Authors

Li, M.,Si, K. (deposition date: 2023-06-29, release date: 2023-08-30)

• Primary citation: Si, K.,He, X.,Chen, L.,Zhang, A.,Guo, C.,Li, M.; The structure of Plasmodium falciparum multidrug resistance protein 1 reveals an N-terminal regulatory domain.; Proc.Natl.Acad.Sci.USA, 120:e2219905120-e2219905120, 2023; PubMed: 37527341; DOI: 10.1073/pnas.2219905120

Experimental method

ELECTRON MICROSCOPY (3.64 Å)