8JVD
Identification of small-molecule binding sites of a ubiquitin-conjugating enzyme-UBE2T through fragment-based screening
Summary for 8JVD
Entry DOI | 10.2210/pdb8jvd/pdb |
Descriptor | Ubiquitin-conjugating enzyme E2 T, 5-fluoranyl-1,3-benzoxazol-2-amine (3 entities in total) |
Functional Keywords | ube2t; ubiquitination; fragment-based drug discovery, ligase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 17982.72 |
Authors | |
Primary citation | Loh, Y.Y.,Anantharajan, J.,Huang, Q.,Xu, W.,Fulwood, J.,Ng, H.Q.,Ng, E.Y.,Gea, C.Y.,Choong, M.L.,Tan, Q.W.,Koh, X.,Lim, W.H.,Nacro, K.,Cherian, J.,Baburajendran, N.,Ke, Z.,Kang, C. Identification of small-molecule binding sites of a ubiquitin-conjugating enzyme-UBE2T through fragment-based screening. Protein Sci., 33:e4904-e4904, 2024 Cited by PubMed: 38358126DOI: 10.1002/pro.4904 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.696 Å) |
Structure validation
Download full validation report