8JUN
Cryo-EM structure of SIDT1 E555Q mutant
Summary for 8JUN
Entry DOI | 10.2210/pdb8jun/pdb |
EMDB information | 36662 |
Descriptor | SID1 transmembrane family member 1, ZINC ION, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (3 entities in total) |
Functional Keywords | sid-1 transmembrane family member 1, crest family, phospholipase d, rna uptake, membrane protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 189495.50 |
Authors | Sun, C.R.,Xu, D.,Li, Q.,Zhou, C.Z.,Chen, Y. (deposition date: 2023-06-26, release date: 2023-11-15, Last modification date: 2024-01-24) |
Primary citation | Sun, C.R.,Xu, D.,Yang, F.,Hou, Z.,Luo, Y.,Zhang, C.Y.,Shan, G.,Huang, G.,Yao, X.,Chen, Y.,Li, Q.,Zhou, C.Z. Human SIDT1 mediates dsRNA uptake via its phospholipase activity. Cell Res., 34:84-87, 2024 Cited by PubMed: 37932444DOI: 10.1038/s41422-023-00889-x PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.38 Å) |
Structure validation
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