8JPN

Cryo-EM structure of succinate receptor bound to cis-epoxysuccinic acid coupling to Gi

Summary for 8JPN

• Entry DOI: 10.2210/pdb8jpn/pdb
• EMDB information: 36484
• Descriptor: Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• Functional Keywords: complex, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 195255.13

Authors

Wang, T.X.,Tang, W.Q.,Li, F.H.,Wang, J.Y. (deposition date: 2023-06-12, release date: 2024-05-22, Last modification date: 2024-10-30)

• Primary citation: Wang, T.,Tang, W.,Zhu, X.,Lv, Z.,Chen, J.,Li, Y.,Sun, X.,Lv, H.,Gu, Q.,Li, F.,Wang, J.; Molecular activation and G protein coupling selectivity of human succinate receptor SUCR1.; Cell Res., 34:590-593, 2024; PubMed: 38744983; DOI: 10.1038/s41422-024-00968-7

Experimental method

ELECTRON MICROSCOPY (2.9 Å)