8JNV
PfDXR - Mn2+ - MAMK89 ternary complex
Summary for 8JNV
Entry DOI | 10.2210/pdb8jnv/pdb |
Related | 8JNW |
Descriptor | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic, MANGANESE (II) ION, [(1~{S})-4-oxidanylidene-4-[oxidanyl(3-phenylpropyl)amino]-1-phenyl-butyl]phosphonic acid, ... (5 entities in total) |
Functional Keywords | inhibitor, complex, isomerase |
Biological source | Plasmodium falciparum HB3 |
Total number of polymer chains | 2 |
Total formula weight | 94644.85 |
Authors | |
Primary citation | Abdullaziz, M.A.,Takada, S.,Illarionov, B.,Pessanha de Carvalho, L.,Sakamoto, Y.,Hofmann, S.,Knak, T.,Kiffe-Delf, A.L.,Mazzone, F.,Pfeffer, K.,Kalscheuer, R.,Bacher, A.,Held, J.,Fischer, M.,Tanaka, N.,Kurz, T. Reverse N -Substituted Hydroxamic Acid Derivatives of Fosmidomycin Target a Previously Unknown Subpocket of 1-Deoxy-d-xylulose 5-Phosphate Reductoisomerase (DXR). Acs Infect Dis., 10:1739-1752, 2024 Cited by PubMed: 38647213DOI: 10.1021/acsinfecdis.4c00100 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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