8JLO

Ulotaront(SEP-363856)-bound hTAAR1-Gs protein complex

Summary for 8JLO

Entry DOI	10.2210/pdb8jlo/pdb
EMDB information	36402
Descriptor	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Soluble cytochrome b562,Trace amine-associated receptor 1, ... (5 entities in total)
Functional Keywords	complex, agonist, membrane protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	147013.77
Authors	Xu, Z.,Guo, L.L.,Zhao, C.,Shen, S.Y.,Sun, J.P.,Shao, Z.H. (deposition date: 2023-06-02, release date: 2023-11-15, Last modification date: 2024-01-03)
Primary citation	Xu, Z.,Guo, L.,Yu, J.,Shen, S.,Wu, C.,Zhang, W.,Zhao, C.,Deng, Y.,Tian, X.,Feng, Y.,Hou, H.,Su, L.,Wang, H.,Guo, S.,Wang, H.,Wang, K.,Chen, P.,Zhao, J.,Zhang, X.,Yong, X.,Cheng, L.,Liu, L.,Yang, S.,Yang, F.,Wang, X.,Yu, X.,Xu, Y.,Sun, J.P.,Yan, W.,Shao, Z. Ligand recognition and G-protein coupling of trace amine receptor TAAR1. Nature, 624:672-681, 2023 Cited by PubMed: 37935376 DOI: 10.1038/s41586-023-06804-z PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.52 Å)

Structure validation