8JG9

Cryo-EM structure of the SaCas9-sgRNA-AcrIIA15-promoter DNA dimer

Summary for 8JG9

• Entry DOI: 10.2210/pdb8jg9/pdb
• EMDB information: 36225
• Descriptor: CRISPR-associated endonuclease Cas9, sgRNA, AcrIIA15, ... (5 entities in total)
• Functional Keywords: ii-a type anti-crispr protein, viral protein
• Biological source: Staphylococcus aureus; More
• Total number of polymer chains: 8
• Total formula weight: 366598.26

Authors

Deng, X.,Wang, Y. (deposition date: 2023-05-20, release date: 2024-02-28, Last modification date: 2024-09-11)

• Primary citation: Deng, X.,Sun, W.,Li, X.,Wang, J.,Cheng, Z.,Sheng, G.,Wang, Y.; An anti-CRISPR that represses its own transcription while blocking Cas9-target DNA binding.; Nat Commun, 15:1806-1806, 2024; PubMed: 38418450; DOI: 10.1038/s41467-024-45987-5

Experimental method

ELECTRON MICROSCOPY (3.82 Å)