8JFN

Crystal structure of enoyl-ACP reductase FabI in complex with NAD+ and crotonyl-ACP from Helicobacter pylori

8JFN の概要

• エントリーDOI: 10.2210/pdb8jfn/pdb
• 分子名称: Enoyl-[acyl-carrier-protein] reductase [NADH], Acyl carrier protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (5 entities in total)
• 機能のキーワード: enoyl-acp reductase, fabi, nad+, crotonyl-acp, helicobacter pylori, biosynthetic protein
• 由来する生物種: Helicobacter pylori; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 39578.81

構造登録者

Song, W.Y.,Zhang, L. (登録日: 2023-05-18, 公開日: 2023-11-15, 最終更新日: 2023-11-22)

• 主引用文献: Zhou, J.,Zhang, L.,Wang, Y.,Song, W.,Huang, Y.,Mu, Y.,Schmitz, W.,Zhang, S.Y.,Lin, H.,Chen, H.Z.,Ye, F.,Zhang, L.; The Molecular Basis of Catalysis by SDR Family Members Ketoacyl-ACP Reductase FabG and Enoyl-ACP Reductase FabI in Type-II Fatty Acid Biosynthesis.; Angew.Chem.Int.Ed.Engl., 62:e202313109-e202313109, 2023; PubMed: 37779101; DOI: 10.1002/anie.202313109

実験手法

X-RAY DIFFRACTION (2.41 Å)