8JDP
Crystal structure of H405A mLDHD in complex with D-2-hydroxyisovaleric acid
Summary for 8JDP
Entry DOI | 10.2210/pdb8jdp/pdb |
Descriptor | Probable D-lactate dehydrogenase, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, DEAMINOHYDROXYVALINE, ... (4 entities in total) |
Functional Keywords | d-lactate dehydrogenase, ldhd, 2-hydroxyacid, oxidoreductase |
Biological source | Mus musculus (house mouse) |
Total number of polymer chains | 1 |
Total formula weight | 51289.47 |
Authors | |
Primary citation | Jin, S.,Chen, X.,Yang, J.,Ding, J. Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14:6638-6638, 2023 Cited by PubMed: 37863926DOI: 10.1038/s41467-023-42456-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
Download full validation report![Download](https://newweb-cs.pages.dev/newweb/media/icons/dl.png)
![Download](https://newweb-cs.pages.dev/newweb/media/icons/dl.png)