8JBC

Crystal Structure of the Csm6 K137A mutant from Thermus thermophilus HB8 in its apo form

Summary for 8JBC

• Entry DOI: 10.2210/pdb8jbc/pdb
• Descriptor: CRISPR system endoribonuclease Csm6, NICKEL (II) ION (3 entities in total)
• Functional Keywords: thermus thermophilus hb8, csm6, endoribonuclease, k137a, hydrolase
• Biological source: Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
• Total number of polymer chains: 2
• Total formula weight: 103171.98

Authors

Lin, Z.,Du, L. (deposition date: 2023-05-08, release date: 2023-12-13, Last modification date: 2024-01-31)

• Primary citation: Du, L.,Zhu, Q.,Lin, Z.; Molecular mechanism of allosteric activation of the CRISPR ribonuclease Csm6 by cyclic tetra-adenylate.; Embo J., 43:304-315, 2024; PubMed: 38177499; DOI: 10.1038/s44318-023-00017-w

Experimental method

X-RAY DIFFRACTION (2.41 Å)