8JBB

Crystal Structure of the Csm6 from Thermus thermophilus HB8 in complex with A2>p

Summary for 8JBB

• Entry DOI: 10.2210/pdb8jbb/pdb
• Descriptor: CRISPR system endoribonuclease Csm6, RNA (5'-R(*AP*(A23))-3') (3 entities in total)
• Functional Keywords: thermus thermophilus hb8, csm6, endoribonuclease, a2>p, hydrolase
• Biological source: Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8); More
• Total number of polymer chains: 4
• Total formula weight: 103724.76

Authors

Lin, Z.,Du, L. (deposition date: 2023-05-08, release date: 2023-12-13, Last modification date: 2024-01-31)

• Primary citation: Du, L.,Zhu, Q.,Lin, Z.; Molecular mechanism of allosteric activation of the CRISPR ribonuclease Csm6 by cyclic tetra-adenylate.; Embo J., 43:304-315, 2024; PubMed: 38177499; DOI: 10.1038/s44318-023-00017-w

Experimental method

X-RAY DIFFRACTION (1.81 Å)