8J9O

Cryo-EM structure of inactive FZD1

Summary for 8J9O

• Entry DOI: 10.2210/pdb8j9o/pdb
• EMDB information: 36112
• Descriptor: Frizzled-1,Soluble cytochrome b562, anti-BRIL Fab Heavy Chain, anti-Fab nanobody, ... (4 entities in total)
• Functional Keywords: frizzled, class-f, fzd1, complex, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 141017.64

Authors

Lin, X.,Xu, F. (deposition date: 2023-05-04, release date: 2024-01-17)

• Primary citation: Zhang, Z.,Lin, X.,Wei, L.,Wu, Y.,Xu, L.,Wu, L.,Wei, X.,Zhao, S.,Zhu, X.,Xu, F.; A framework for Frizzled-G protein coupling and implications to the PCP signaling pathways.; Cell Discov, 10:3-3, 2024; PubMed: 38182578; DOI: 10.1038/s41421-023-00627-y

Experimental method

ELECTRON MICROSCOPY (3.4 Å)