8J7T
Cryo-EM structure of hZnT7-Fab complex in zinc-unbound state, determined in outward-facing conformation
Summary for 8J7T
Entry DOI | 10.2210/pdb8j7t/pdb |
EMDB information | 36048 |
Descriptor | Zinc transporter 7, Light chain of YN7114-08 Fab, Heavy chain of YN7114-08 Fab (3 entities in total) |
Functional Keywords | zinc, proton, transporter, golgi apparatus, metal transporter, histidine-rich loop, metal transport |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 184237.90 |
Authors | |
Primary citation | Bui, H.B.,Watanabe, S.,Nomura, N.,Liu, K.,Uemura, T.,Inoue, M.,Tsutsumi, A.,Fujita, H.,Kinoshita, K.,Kato, Y.,Iwata, S.,Kikkawa, M.,Inaba, K. Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus. Nat Commun, 14:4770-4770, 2023 Cited by PubMed: 37553324DOI: 10.1038/s41467-023-40521-5 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.2 Å) |
Structure validation
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