8J66

Crystal structure of glycosyltransferase SgUGT94-289-3 in complex with M3, state 2

Summary for 8J66

• Entry DOI: 10.2210/pdb8j66/pdb
• Descriptor: Glycosyltransferase, URIDINE-5'-DIPHOSPHATE, (2S,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[[(2R,3S,4S,5R,6S)-6-[(3R,6S)-6-[(3S,8S,9R,10R,11S,13R,14S,17S)-3-[(2R,3R,4S,5S,6S)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-4,4,9,13,14-pentamethyl-11-oxidanyl-2,3,7,8,10,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-2-oxidanyl-heptan-3-yl]oxy-3,4,5-tris(oxidanyl)oxan-2-yl]methoxy]oxane-3,4,5-triol, ... (4 entities in total)
• Functional Keywords: mogroside, ugt, biosynthesis, transferase
• Biological source: Siraitia grosvenorii
• Total number of polymer chains: 1
• Total formula weight: 53939.26

Authors

Li, M.,Zhang, S.,Cui, S. (deposition date: 2023-04-24, release date: 2024-05-29, Last modification date: 2024-08-14)

• Primary citation: Cui, S.,Zhang, S.,Wang, N.,Su, X.,Luo, Z.,Ma, X.,Li, M.; Structural insights into the catalytic selectivity of glycosyltransferase SgUGT94-289-3 towards mogrosides.; Nat Commun, 15:6423-6423, 2024; PubMed: 39080270; DOI: 10.1038/s41467-024-50662-w

Experimental method

X-RAY DIFFRACTION (2.27 Å)