8ITP
Crystal structure of USP47 catalytic domain complex with ubiquitin
Summary for 8ITP
| Entry DOI | 10.2210/pdb8itp/pdb |
| Descriptor | Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 47, ZINC ION (3 entities in total) |
| Functional Keywords | ubiquitin specific protease, hydrolase-inhibitor complex, hydrolase/inhibitor |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 132420.25 |
| Authors | Kim, E.E.,Shin, S.C. (deposition date: 2023-03-22, release date: 2024-03-27, Last modification date: 2024-05-08) |
| Primary citation | Shin, S.C.,Park, J.,Kim, K.H.,Yoon, J.M.,Cho, J.,Ha, B.H.,Oh, Y.,Choo, H.,Song, E.J.,Kim, E.E. Structural and functional characterization of USP47 reveals a hot spot for inhibitor design. Commun Biol, 6:970-970, 2023 Cited by PubMed: 37740002DOI: 10.1038/s42003-023-05345-5 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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