8ISP
Crystal structure of extended-spectrum class A beta-lactamase, CESS-1 E166Q acylated by cephalexin
Summary for 8ISP
Entry DOI | 10.2210/pdb8isp/pdb |
Related | 1O7E |
Descriptor | Beta-lactamase, (R)-2-((R)-((R)-2-amino-2-phenylacetamido)(carboxy)methyl)-5-methyl-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid (3 entities in total) |
Functional Keywords | hydrolase, extended-spectrum class a beta-lactamase |
Biological source | Stenotrophomonas sp. KCTC 12332 |
Total number of polymer chains | 1 |
Total formula weight | 29017.68 |
Authors | Jeong, B.G.,Kim, M.Y.,Jeong, C.S.,Do, H.W.,Lee, J.H.,Cha, S.S. (deposition date: 2023-03-21, release date: 2024-05-15, Last modification date: 2024-10-16) |
Primary citation | Jeong, B.G.,Kim, M.Y.,Jeong, C.S.,Do, H.,Hwang, J.,Lee, J.H.,Cha, S.S. Characterization of the extended substrate spectrum of the class A beta-lactamase CESS-1 from Stenotrophomonas sp. and structure-based investigation into its substrate preference. Int J Antimicrob Agents, 63:107171-107171, 2024 Cited by PubMed: 38588869DOI: 10.1016/j.ijantimicag.2024.107171 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.11 Å) |
Structure validation
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