8IPM

The structure of human mitochondrial methyltransferase METTL15 with h44_RNA, RBFA and SAM

Summary for 8IPM

• Entry DOI: 10.2210/pdb8ipm/pdb
• Descriptor: Putative ribosome-binding factor A, mitochondrial, 12S rRNA N4-methylcytidine (m4C) methyltransferase, RNA (5'-R(*CP*GP*AP*CP*CP*GP*CP*CP*CP*GP*UP*AP*AP*CP*GP*GP*UP*CP*G)-3'), ... (4 entities in total)
• Functional Keywords: human mitochondrial methyltransferase mettl15, ribosomal protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 48033.00

Authors

Lv, M.Q.,Zhou, W.W. (deposition date: 2023-03-14, release date: 2024-01-03, Last modification date: 2024-02-14)

• Primary citation: Lv, M.,Zhou, W.,Hao, Y.,Li, F.,Zhang, H.,Yao, X.,Shi, Y.,Zhang, L.; Structural insights into the specific recognition of mitochondrial ribosome-binding factor hsRBFA and 12 S rRNA by methyltransferase METTL15.; Cell Discov, 10:11-11, 2024; PubMed: 38291322; DOI: 10.1038/s41421-023-00634-z

Experimental method

X-RAY DIFFRACTION (3.1 Å)