8IMF
Human cGAS catalytic domain bound with baicalein
Summary for 8IMF
Entry DOI | 10.2210/pdb8imf/pdb |
Descriptor | Cyclic GMP-AMP synthase, ZINC ION, 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one, ... (4 entities in total) |
Functional Keywords | cgas, inhibitor, baicalein, immune system |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 85919.59 |
Authors | |
Primary citation | Li, J.,Xiong, M.,Liu, J.,Zhang, F.,Li, M.,Zhao, W.,Xu, Y. Discovery of novel cGAS inhibitors based on natural flavonoids. Bioorg.Chem., 140:106802-106802, 2023 Cited by PubMed: 37666112DOI: 10.1016/j.bioorg.2023.106802 PDB entries with the same primary citation |
Experimental method |
Structure validation
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