8IKE

Transcription factors LMX1a mutant-R199A homeobox domain complex with Wnt1 promoter

Summary for 8IKE

• Entry DOI: 10.2210/pdb8ike/pdb
• Descriptor: DNA (5'-D(*CP*CP*AP*TP*AP*TP*TP*TP*AP*AP*TP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*GP*AP*AP*GP*AP*TP*TP*AP*AP*AP*TP*AP*TP*G)-3'), LMX1A factor, ... (4 entities in total)
• Functional Keywords: protein-dsdna complex, dna binding protein, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 16150.25

Authors

Lv, M.Q.,Lin, L.Q. (deposition date: 2023-02-28, release date: 2024-03-06)

• Primary citation: Lv, M.Q.,Lin, L.Q.; Structural insights into the recognition of the A/T-rich motif in target gene promoters by the LMX1a homeobox domain; Febs J., 2024

Experimental method

X-RAY DIFFRACTION (2.6 Å)