8IK3

Structure of Stimulator of interferon genes/ligand complex

Summary for 8IK3

• Entry DOI: 10.2210/pdb8ik3/pdb
• Related: 8IK0
• EMDB information: 35504
• Descriptor: Stimulator of interferon genes protein,Immune protein Tsi3, cGAMP (2 entities in total)
• Functional Keywords: complex, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 467921.61

Authors

Lu, D.F.,Shang, G.J. (deposition date: 2023-02-28, release date: 2023-05-17, Last modification date: 2024-05-01)

• Primary citation: Liu, S.,Yang, B.,Hou, Y.,Cui, K.,Yang, X.,Li, X.,Chen, L.,Liu, S.,Zhang, Z.,Jia, Y.,Xie, Y.,Xue, Y.,Li, X.,Yan, B.,Wu, C.,Deng, W.,Qi, J.,Lu, D.,Gao, G.F.,Wang, P.,Shang, G.; The mechanism of STING autoinhibition and activation.; Mol.Cell, 83:1502-1518.e10, 2023; PubMed: 37086726; DOI: 10.1016/j.molcel.2023.03.029

Experimental method

ELECTRON MICROSCOPY (3.3 Å)