8IFL
Cryo-EM structure of tetrameric SPARTA gRNA-ssDNA target complex in state 1
Summary for 8IFL
| Entry DOI | 10.2210/pdb8ifl/pdb |
| EMDB information | 35420 |
| Descriptor | TIR domain-containing protein, Piwi domain-containing protein, guide RNA, ... (5 entities in total) |
| Functional Keywords | rna binding protein-rna-dna complex, rna binding protein/rna/dna |
| Biological source | Thermoflavifilum thermophilum More |
| Total number of polymer chains | 16 |
| Total formula weight | 503703.49 |
| Authors | Zhang, J.T.,Jia, N. (deposition date: 2023-02-18, release date: 2024-01-17, Last modification date: 2024-04-10) |
| Primary citation | Zhang, J.T.,Wei, X.Y.,Cui, N.,Tian, R.,Jia, N. Target ssDNA activates the NADase activity of prokaryotic SPARTA immune system. Nat.Chem.Biol., 20:503-511, 2024 Cited by PubMed: 37932528DOI: 10.1038/s41589-023-01479-z PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.11 Å) |
Structure validation
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