8IFJ

Crystal structure of pyrrolysyl-tRNA synthetase from methanogenic archaeon ISO4-G1

8IFJ の概要

• エントリーDOI: 10.2210/pdb8ifj/pdb
• 分子名称: Pyrrolysyl-tRNA synthetase PylS (2 entities in total)
• 機能のキーワード: non-canonical amino acids, genetic code expansion, trna, translation
• 由来する生物種: methanogenic archaeon mixed culture ISO4-G1
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 312564.69

構造登録者

Yanagisawa, T.,Tanabe, H.,Yokoyama, S. (登録日: 2023-02-18, 公開日: 2023-03-15, 最終更新日: 2024-05-29)

• 主引用文献: Yanagisawa, T.,Seki, E.,Tanabe, H.,Fujii, Y.,Sakamoto, K.,Yokoyama, S.; Crystal Structure of Pyrrolysyl-tRNA Synthetase from a Methanogenic Archaeon ISO4-G1 and Its Structure-Based Engineering for Highly-Productive Cell-Free Genetic Code Expansion with Non-Canonical Amino Acids.; Int J Mol Sci, 24:-, 2023; PubMed: 37047230; DOI: 10.3390/ijms24076256

実験手法

X-RAY DIFFRACTION (2.78 Å)