8I7P

Crystal structure of Ricin A chain bound with N2-(2-amino-4-oxo-3,4-dihydropteridine-7-carbonyl)glycyl-L-tyrosine

Summary for 8I7P

Entry DOI	10.2210/pdb8i7p/pdb
Descriptor	Ricin A chain, 6-(2-ethyl-4-hydroxyphenyl)-1H-indazole-3-carboxamide, SULFATE ION, ... (4 entities in total)
Functional Keywords	toxin, inhibitor, hydrolase
Biological source	Ricinus communis (castor bean) More
Total number of polymer chains	2
Total formula weight	31516.31
Authors	Goto, M.,Sakamoto, N.,Higashi, S.,Kawata, R.,Nagatsu, K.,Saito, R. (deposition date: 2023-02-01, release date: 2023-09-20)
Primary citation	Goto, M.,Sakamoto, N.,Higashi, S.,Kawata, R.,Nagatsu, K.,Saito, R. Crystal structure of ricin toxin A chain complexed with a highly potent pterin-based small-molecular inhibitor. J Enzyme Inhib Med Chem, 38:2219038-2219038, 2023 Cited by PubMed: 37259593 DOI: 10.1080/14756366.2023.2219038 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation