8I5H

Crystal structure of SARS-CoV-2 delta variant spike receptor-binding domain (RBD) in complex with NCV2SG48 Fab

8I5H の概要

• エントリーDOI: 10.2210/pdb8i5h/pdb
• 関連するPDBエントリー: 7WN2 7WNB 7YOW
• 分子名称: Spike protein S1, Fab Heavy chain, Fab Light chain, ... (5 entities in total)
• 機能のキーワード: spike, coronavirus, viral protein, fab, viral protein-immune system complex, virus, viral protein/immune system
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2; 詳細
• タンパク質・核酸の鎖数: 9
• 化学式量合計: 209862.65

構造登録者

Yamamoto, A.,Higashiura, A. (登録日: 2023-01-25, 公開日: 2023-04-19)

• 主引用文献: Shitaoka, K.,Higashiura, A.,Kawano, Y.,Yamamoto, A.,Mizoguchi, Y.,Hashiguchi, T.,Nishimichi, N.,Huang, S.,Ito, A.,Ohki, S.,Kanda, M.,Taniguchi, T.,Yoshizato, R.,Azuma, H.,Kitajima, Y.,Yokosaki, Y.,Okada, S.,Sakaguchi, T.,Yasuda, T.; Structural basis of spike RBM-specific human antibodies counteracting broad SARS-CoV-2 variants.; Commun Biol, 6:395-395, 2023; PubMed: 37041231; DOI: 10.1038/s42003-023-04782-6

実験手法

X-RAY DIFFRACTION (2.38 Å)