8I16
Crystal structure of the selenomethionine (SeMet)-derived Cas12g (D513A) mutant
Summary for 8I16
| Entry DOI | 10.2210/pdb8i16/pdb |
| Descriptor | Cas12g, ZINC ION (3 entities in total) |
| Functional Keywords | cas12g, crispr, cas, cas12, rnp, rna binding protein |
| Biological source | Lachnospiraceae bacterium ND2006 |
| Total number of polymer chains | 1 |
| Total formula weight | 91377.93 |
| Authors | Zhang, B.,Chen, J.,Ye, Y.M.,OuYang, S.Y. (deposition date: 2023-01-12, release date: 2023-08-30, Last modification date: 2023-11-15) |
| Primary citation | Liu, M.,Li, Z.,Chen, J.,Lin, J.,Lu, Q.,Ye, Y.,Zhang, H.,Zhang, B.,Ouyang, S. Structural transitions upon guide RNA binding and their importance in Cas12g-mediated RNA cleavage. Plos Genet., 19:e1010930-e1010930, 2023 Cited by PubMed: 37729124DOI: 10.1371/journal.pgen.1010930 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.24 Å) |
Structure validation
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