8I0W

The cryo-EM structure of human C complex

This is a non-PDB format compatible entry.

Summary for 8I0W

• Entry DOI: 10.2210/pdb8i0w/pdb
• EMDB information: 35113
• Descriptor: Pre-mRNA-processing-splicing factor 8, Pre-mRNA-splicing factor SYF1, Crooked neck-like protein 1, ... (52 entities in total)
• Functional Keywords: spliceosome, rna splicing, prp16, branching, splicing
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 58
• Total formula weight: 3241207.90

Authors

Zhan, X.,Lu, Y.,Shi, Y. (deposition date: 2023-01-11, release date: 2024-07-31, Last modification date: 2024-08-07)

• Primary citation: Zhan, X.,Lu, Y.,Shi, Y.; Molecular basis for the activation of human spliceosome.; Nat Commun, 15:6348-6348, 2024; PubMed: 39068178; DOI: 10.1038/s41467-024-50785-0

Experimental method

ELECTRON MICROSCOPY (3.4 Å)