8HYB
Crystal structure of B1 IMP-1 MBL in complex with 2-amino-5-phenethylthiazole-4-carboxylic acid
Summary for 8HYB
Entry DOI | 10.2210/pdb8hyb/pdb |
Descriptor | Beta-lactamase, ZINC ION, 2-azanyl-5-(2-phenylethyl)-1,3-thiazole-4-carboxylic acid, ... (6 entities in total) |
Functional Keywords | beta-lactamase class b imp-1, hydrolase |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 4 |
Total formula weight | 98671.25 |
Authors | |
Primary citation | Yan, Y.-H.,Zhu, K.-R.,Yang, L.-L.,Li, G.-B. 2-Aminothiazole-4-carboxylic acids as cross-class metallo-beta-lactamase inhibitors by mimicking beta-lactam hydrolysate binding To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.193 Å) |
Structure validation
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