8HY9

Bacterial STING from Riemerella anatipestifer in complex with 3'3'-c-di-GMP

Summary for 8HY9

Entry DOI	10.2210/pdb8hy9/pdb
Descriptor	CD-NTase-associated protein 12, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CALCIUM ION, ... (4 entities in total)
Functional Keywords	cd-ntase-associated protein 12, signaling protein
Biological source	Riemerella anatipestifer Yb2
Total number of polymer chains	1
Total formula weight	19294.43
Authors	Wang, Y.-C.,Yang, C.-S.,Hou, M.-H.,Chen, Y. (deposition date: 2023-01-06, release date: 2024-01-10, Last modification date: 2024-01-24)
Primary citation	Hou, M.H.,Wang, Y.C.,Yang, C.S.,Liao, K.F.,Chang, J.W.,Shih, O.,Yeh, Y.Q.,Sriramoju, M.K.,Weng, T.W.,Jeng, U.S.,Hsu, S.D.,Chen, Y. Structural insights into the regulation, ligand recognition, and oligomerization of bacterial STING. Nat Commun, 14:8519-8519, 2023 Cited by PubMed: 38129386 DOI: 10.1038/s41467-023-44052-x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.462 Å)

Structure validation