8HX3

crystal structure of secreted coleopteran active protein (Sip)

This is a non-PDB format compatible entry.

Summary for 8HX3

• Entry DOI: 10.2210/pdb8hx3/pdb
• Descriptor: Secreted coleopteran active protein, GLYCEROL (3 entities in total)
• Functional Keywords: secreted coleopteran active protein, toxin
• Biological source: Bacillus thuringiensis
• Total number of polymer chains: 2
• Total formula weight: 72600.69

Authors

Chen, Z.,Jiang, K.,Gao, X. (deposition date: 2023-01-03, release date: 2023-07-12, Last modification date: 2023-10-25)

Primary citation

Chen, Z.,Shi, Y.,Wang, D.,Liu, X.,Jiao, X.,Gao, X.,Jiang, K.
Structural insight into Bacillus thuringiensis Sip1Ab reveals its similarity to ETX_MTX2 family beta-pore-forming toxin.
Pest Manag Sci, 79:4264-4273, 2023

PubMed Abstract: Microbially derived, protein-based biopesticides are an important approach for sustainable pest management. The secreted insecticidal proteins (Sips) produced by the bacterium Bacillus thuringiensis exhibit potent insecticidal activity against coleopteran pests and are, therefore, attractive as candidate biopesticides. However, the modes-of-action of Sips are unclear as comprehensive structural information for these proteins is lacking.

PubMed: 37341620
DOI: 10.1002/ps.7622

Experimental method

X-RAY DIFFRACTION (2.28 Å)