8HUW
Crystal structure of SARS-Cov-2 main protease K90R mutant in complex with S217622
Summary for 8HUW
Entry DOI | 10.2210/pdb8huw/pdb |
Descriptor | 3C-like proteinase nsp5, 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione (3 entities in total) |
Functional Keywords | viral protein-inhibitor complex, k90r mutant, viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2) |
Total number of polymer chains | 2 |
Total formula weight | 67417.44 |
Authors | |
Primary citation | Lin, C.,Jiang, H.,Li, W.,Zeng, P.,Zhou, X.,Zhang, J.,Li, J. Structural basis for the inhibition of coronaviral main proteases by ensitrelvir. Structure, 31:1016-1024.e3, 2023 Cited by PubMed: 37421945DOI: 10.1016/j.str.2023.06.010 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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