8HT7

The N-terminal region of Cdc6 specifically recognizes human DNA G-quadruplex

Summary for 8HT7

• Entry DOI: 10.2210/pdb8ht7/pdb
• Descriptor: DNA (5'-D(*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*TP*GP*GP*G)-3'), GLN-ALA-GLN-ALA-THR-ILE-SER-PHE-PRO-LYS-ARG-LYS-LEU-SER-TRP (2 entities in total)
• Functional Keywords: dna replication, g-quadruplex, intrinsically disordered region, dna binding protein
• Biological source: Homo sapiens; More
• Total number of polymer chains: 2
• Total formula weight: 8425.33

Authors

Liu, C.,Zhu, G.,Geng, Y.,Xu, N. (deposition date: 2022-12-20, release date: 2023-12-27, Last modification date: 2024-05-22)

• Primary citation: Geng, Y.,Liu, C.,Xu, N.,Shi, X.,Suen, M.C.,Zhou, B.,Yan, B.,Wu, C.,Li, H.,Song, Y.,Chen, X.,Wang, Z.,Cai, Q.,Zhu, G.; The N-terminal region of Cdc6 specifically recognizes human DNA G-quadruplex.; Int.J.Biol.Macromol., 260:129487-129487, 2024; PubMed: 38237821; DOI: 10.1016/j.ijbiomac.2024.129487

Experimental method

SOLUTION NMR