8HSC
Gi bound Orphan GPR20 complex with Fab046 in ligand-free state
Summary for 8HSC
Entry DOI | 10.2210/pdb8hsc/pdb |
EMDB information | 34993 |
Descriptor | light chain of Fab046, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (7 entities in total) |
Functional Keywords | orphan receptor, gpcr, gpr20, gi-coupled, gpr20-gi-fab046, membrane protein |
Biological source | Rattus More |
Total number of polymer chains | 7 |
Total formula weight | 224707.03 |
Authors | |
Primary citation | Lin, X.,Jiang, S.,Wu, Y.,Wei, X.,Han, G.W.,Wu, L.,Liu, J.,Chen, B.,Zhang, Z.,Zhao, S.,Cherezov, V.,Xu, F. The activation mechanism and antibody binding mode for orphan GPR20. Cell Discov, 9:23-23, 2023 Cited by PubMed: 36849514DOI: 10.1038/s41421-023-00520-8 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.22 Å) |
Structure validation
Download full validation report