8HNE

Crystal structure of the ancestral GH19 chitinase Anc4

Summary for 8HNE

Entry DOI	10.2210/pdb8hne/pdb
Descriptor	Anc4, ancestral GH19 chitinase, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, ... (4 entities in total)
Functional Keywords	gh19 chitinase, hydrolase
Biological source	synthetic construct
Total number of polymer chains	1
Total formula weight	24691.50
Authors	Kozome, D.,Laurino, P. (deposition date: 2022-12-07, release date: 2023-12-13, Last modification date: 2024-09-04)
Primary citation	Kozome, D.,Sljoka, A.,Laurino, P. Remote loop evolution reveals a complex biological function for chitinase enzymes beyond the active site. Nat Commun, 15:3227-3227, 2024 Cited by PubMed: 38622119 DOI: 10.1038/s41467-024-47588-8 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.13 Å)

Structure validation