8HN6

Crystal structure of monoclonal antibody complexed with SARS-CoV-2 RBD

8HN6 の概要

• エントリーDOI: 10.2210/pdb8hn6/pdb
• 分子名称: Heavy chain of monoclonal antibody 3G10, Light chain of monoclonal antibody 3G10, Spike protein S1, ... (4 entities in total)
• 機能のキーワード: sars-cov-2, rbd, monoclonal antibody, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 92739.99

構造登録者

Qi, J.,Chen, Y. (登録日: 2022-12-07, 公開日: 2023-05-17, 最終更新日: 2023-06-07)

• 主引用文献: Wang, Z.,Li, D.,Chen, Y.,Sun, Y.,Jin, C.,Hu, C.,Feng, Y.,Su, J.,Ren, L.,Hao, Y.,Wang, S.,Zhu, M.,Liu, Y.,Qi, J.,Zhu, B.,Shao, Y.; Characterization of RBD-specific cross-neutralizing antibodies responses against SARS-CoV-2 variants from COVID-19 convalescents.; Front Immunol, 14:1160283-1160283, 2023; PubMed: 37234155; DOI: 10.3389/fimmu.2023.1160283

実験手法

X-RAY DIFFRACTION (2.07 Å)