8HMS

Crystal Structure of PKM2 mutant C474S

8HMS の概要

• エントリーDOI: 10.2210/pdb8hms/pdb
• 分子名称: Pyruvate kinase PKM, 1,6-di-O-phosphono-beta-D-fructofuranose, OXALATE ION, ... (7 entities in total)
• 機能のキーワード: pkm2, hydroxylation, kinase, glycolysis, tumour promoting, warburg effect, transferase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 242893.46

構造登録者

Upadhyay, S.,Kumar, A.,Patel, A.K. (登録日: 2022-12-05, 公開日: 2023-01-11, 最終更新日: 2024-05-29)

• 主引用文献: Upadhyay, S.,Kumar, A.,Patel, A.K.; Structural and mechanistic insights into cancer patient-derived mutations in Pyruvate Kinase muscle isoform 2; To Be Published,

実験手法

X-RAY DIFFRACTION (2.1 Å)