8HMQ
Crystal Structure of PKM2 mutant P403A
Summary for 8HMQ
Entry DOI | 10.2210/pdb8hmq/pdb |
Descriptor | Pyruvate kinase PKM, OXALATE ION, GLYCEROL, ... (7 entities in total) |
Functional Keywords | pkm2, hydroxylation, kinase, glycolysis, tumour promoting, warburg effect, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 243195.01 |
Authors | Upadhyay, S.,Kumar, A.,Patel, A.K. (deposition date: 2022-12-05, release date: 2023-01-11, Last modification date: 2024-05-29) |
Primary citation | Upadhyay, S.,Kumar, A.,Patel, A.K. Structural and mechanistic insights into cancer patient-derived mutations in Pyruvate Kinase muscle isoform 2 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)