8HIK

The TPP-bound BRIL-SLC19A1/Fab/Nb ternary complex

Summary for 8HIK

• Entry DOI: 10.2210/pdb8hik/pdb
• EMDB information: 34819
• Descriptor: BRIL-SLC19A1 chimera, Anti-BRIL Fab heavy chain, Anti-Fab nanobody, ... (5 entities in total)
• Functional Keywords: slc19a1, rfc, transporter, folates, 5-mthf, tpp, transport protein
• Biological source: Escherichia coli; More
• Total number of polymer chains: 4
• Total formula weight: 145544.02

Authors

Zhang, Z.,Dang, Y. (deposition date: 2022-11-20, release date: 2022-12-21, Last modification date: 2023-01-11)

• Primary citation: Dang, Y.,Zhou, D.,Du, X.,Zhao, H.,Lee, C.H.,Yang, J.,Wang, Y.,Qin, C.,Guo, Z.,Zhang, Z.; Molecular mechanism of substrate recognition by folate transporter SLC19A1.; Cell Discov, 8:141-141, 2022; PubMed: 36575193; DOI: 10.1038/s41421-022-00508-w

Experimental method

ELECTRON MICROSCOPY (3.72 Å)