8HIA

Structure of transforming growth factor beta induced protein (TGFBIp) G623R fibril

Summary for 8HIA

• Entry DOI: 10.2210/pdb8hia/pdb
• Related: 8HGA
• EMDB information: 34813
• Descriptor: Transforming growth factor-beta-induced protein ig-h3 (1 entity in total)
• Functional Keywords: pathological fibrils, tgfbi related corneal dystrophy, protein fibril
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 20
• Total formula weight: 50958.44

Authors

Low, J.Y.K.,Pervushin, K. (deposition date: 2022-11-19, release date: 2023-07-26, Last modification date: 2024-02-21)

• Primary citation: Low, J.Y.K.,Shi, X.,Anandalakshmi, V.,Neo, D.,Peh, G.S.L.,Koh, S.K.,Zhou, L.,Abdul Rahim, M.K.,Boo, K.,Lee, J.,Mohanram, H.,Alag, R.,Mu, Y.,Mehta, J.S.,Pervushin, K.; Release of frustration drives corneal amyloid disaggregation by brain chaperone.; Commun Biol, 6:348-348, 2023; PubMed: 36997596; DOI: 10.1038/s42003-023-04725-1

Experimental method

ELECTRON MICROSCOPY (4.9 Å)