8HHZ

SARS-CoV-2 Omicron BA.1 Spike in complex with IY-2A

8HHZ の概要

• エントリーDOI: 10.2210/pdb8hhz/pdb
• EMDBエントリー: 34808
• 分子名称: Spike glycoprotein, IY-2A Fab heavy chain, IY-2A Fab light chain (3 entities in total)
• 機能のキーワード: spike, omicron variant, ba.1, rbd, monoclonal antibody, fab, iy-2a, class 4, viral protein, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); 詳細
• タンパク質・核酸の鎖数: 9
• 化学式量合計: 560579.25

構造登録者

Chen, X.,Mohapatra, A.,Wu, Y.-M. (登録日: 2022-11-17, 公開日: 2023-02-01)

• 主引用文献: Huang, K.A.,Chen, X.,Mohapatra, A.,Nguyen, H.T.V.,Schimanski, L.,Tan, T.K.,Rijal, P.,Vester, S.K.,Hills, R.A.,Howarth, M.,Keeffe, J.R.,Cohen, A.A.,Kakutani, L.M.,Wu, Y.M.,Shahed-Al-Mahmud, M.,Chou, Y.C.,Bjorkman, P.J.,Townsend, A.R.,Ma, C.; Structural basis for a conserved neutralization epitope on the receptor-binding domain of SARS-CoV-2.; Nat Commun, 14:311-311, 2023; PubMed: 36658148; DOI: 10.1038/s41467-023-35949-8

実験手法

ELECTRON MICROSCOPY (4.28 Å)