8HFP
Crystal structure of the methyl-CpG-binding domain of SETDB2 in complex with the cysteine-rich domain of C11orf46 protein
Summary for 8HFP
Entry DOI | 10.2210/pdb8hfp/pdb |
Descriptor | ARL14 effector protein, Histone-lysine N-methyltransferase SETDB2, ZINC ION, ... (5 entities in total) |
Functional Keywords | complex, zn-binding, heterochromatin, histone methylation, transcription |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 42934.61 |
Authors | Mahana, Y.,Ariyoshi, M.,Shirakawa, M. (deposition date: 2022-11-11, release date: 2023-11-22, Last modification date: 2024-06-26) |
Primary citation | Mahana, Y.,Ariyoshi, M.,Nozawa, R.S.,Shibata, S.,Nagao, K.,Obuse, C.,Shirakawa, M. Structural evidence for protein-protein interaction between the non-canonical methyl-CpG-binding domain of SETDB proteins and C11orf46. Structure, 32:304-315.e5, 2024 Cited by PubMed: 38159574DOI: 10.1016/j.str.2023.12.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.82 Å) |
Structure validation
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