8HFP

Crystal structure of the methyl-CpG-binding domain of SETDB2 in complex with the cysteine-rich domain of C11orf46 protein

8HFP の概要

• エントリーDOI: 10.2210/pdb8hfp/pdb
• 分子名称: ARL14 effector protein, Histone-lysine N-methyltransferase SETDB2, ZINC ION, ... (5 entities in total)
• 機能のキーワード: complex, zn-binding, heterochromatin, histone methylation, transcription
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 42934.61

構造登録者

Mahana, Y.,Ariyoshi, M.,Shirakawa, M. (登録日: 2022-11-11, 公開日: 2023-11-22, 最終更新日: 2024-06-26)

• 主引用文献: Mahana, Y.,Ariyoshi, M.,Nozawa, R.S.,Shibata, S.,Nagao, K.,Obuse, C.,Shirakawa, M.; Structural evidence for protein-protein interaction between the non-canonical methyl-CpG-binding domain of SETDB proteins and C11orf46.; Structure, 32:304-315.e5, 2024; PubMed: 38159574; DOI: 10.1016/j.str.2023.12.001

実験手法

X-RAY DIFFRACTION (1.82 Å)