8HFN

Crystal Structure of Mycobacterium smegmatis MshC in Complex with Compound 7b

Summary for 8HFN

• Entry DOI: 10.2210/pdb8hfn/pdb
• Related: 8HFM
• Descriptor: L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase, CALCIUM ION, N-[(3M)-3-(6-methoxypyridin-3-yl)benzene-1-sulfonyl]-L-cysteinamide, ... (5 entities in total)
• Functional Keywords: rossmann fold, ligase, inhibitor
• Biological source: Mycolicibacterium smegmatis MC2 155
• Total number of polymer chains: 1
• Total formula weight: 46021.61

Authors

Pang, L.,Weeks, S.D.,Strelkov, S.V. (deposition date: 2022-11-11, release date: 2022-12-07, Last modification date: 2023-10-25)

• Primary citation: Pang, L.,Lenders, S.,Osipov, E.M.,Weeks, S.D.,Rozenski, J.,Piller, T.,Cappoen, D.,Strelkov, S.V.,Van Aerschot, A.; Structural Basis of Cysteine Ligase MshC Inhibition by Cysteinyl-Sulfonamides.; Int J Mol Sci, 23:-, 2022; PubMed: 36499418; DOI: 10.3390/ijms232315095

Experimental method

X-RAY DIFFRACTION (1.98 Å)