8HFJ

Crystal Structure of CbAR mutant (H162F) in complex with NADP+ and a bulky 1,3-cyclodiketone

8HFJ の概要

• エントリーDOI: 10.2210/pdb8hfj/pdb
• 分子名称: Versicolorin reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 2-methyl-2-[(4-methylphenyl)methyl]cyclopentane-1,3-dione, ... (4 entities in total)
• 機能のキーワード: anthrol reductase, chiral alcohol, emodin, oxidoreductase
• 由来する生物種: Cercospora sp. JNU001
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 123905.93

構造登録者

Hou, X.D.,Yin, D.J.,Rao, Y.J. (登録日: 2022-11-10, 公開日: 2023-06-07, 最終更新日: 2023-11-08)

• 主引用文献: Hou, X.,Xu, H.,Yuan, Z.,Deng, Z.,Fu, K.,Gao, Y.,Liu, C.,Zhang, Y.,Rao, Y.; Structural analysis of an anthrol reductase inspires enantioselective synthesis of enantiopure hydroxycycloketones and beta-halohydrins.; Nat Commun, 14:353-353, 2023; PubMed: 36681664; DOI: 10.1038/s41467-023-36064-4

実験手法

X-RAY DIFFRACTION (2.75 Å)