8HES

Crystal structure of SARS-CoV-2 RBD and NIV-10 complex

8HES の概要

• エントリーDOI: 10.2210/pdb8hes/pdb
• EMDBエントリー: 33823
• 分子名称: NIV-10 Fab H-chain, Spike protein S1, NIV-10 Fab L-chain, ... (5 entities in total)
• 機能のキーワード: virus, sars-cov-2, rbd, spike, antibody, igg, neutralizing antibody, complex, viral protein, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 74147.56

構造登録者

Moriyama, S.,Anraku, Y.,Taminishi, S.,Adachi, Y.,Kuroda, D.,Higuchi, Y.,Kotaki, R.,Tonouchi, K.,Yumoto, K.,Suzuki, T.,Kita, S.,Someya, T.,Fukuhara, H.,Kuroda, Y.,Yamamoto, T.,Onodera, T.,Fukushi, S.,Maeda, K.,Nakamura-Uchiyama, F.,Hashiguchi, T.,Hoshino, A.,Maenaka, K.,Takahashi, Y. (登録日: 2022-11-08, 公開日: 2023-11-08)

• 主引用文献: Moriyama, S.,Anraku, Y.,Taminishi, S.,Adachi, Y.,Kuroda, D.,Kita, S.,Higuchi, Y.,Kirita, Y.,Kotaki, R.,Tonouchi, K.,Yumoto, K.,Suzuki, T.,Someya, T.,Fukuhara, H.,Kuroda, Y.,Yamamoto, T.,Onodera, T.,Fukushi, S.,Maeda, K.,Nakamura-Uchiyama, F.,Hashiguchi, T.,Hoshino, A.,Maenaka, K.,Takahashi, Y.; Structural delineation and computational design of SARS-CoV-2-neutralizing antibodies against Omicron subvariants.; Nat Commun, 14:4198-4198, 2023; PubMed: 37452031; DOI: 10.1038/s41467-023-39890-8

実験手法

X-RAY DIFFRACTION (2.2 Å)