8HDZ

Monkeypox virus DNA replication holoenzyme F8, A22 and E4 complex in an apo form

8HDZ の概要

• エントリーDOI: 10.2210/pdb8hdz/pdb
• EMDBエントリー: 34684
• 分子名称: F8 DNA polymerase, A22 DNA replication processivity factor, E4 uracil-DNA glycosylase (3 entities in total)
• 機能のキーワード: dna replication machinery, f8, a22, e4, dna polymerase, b-family dna polymerase, uracil-dna glycosylase, mpxv, orthopoxvirus, poxviridae, dna processivity factor, viral protein
• 由来する生物種: Monkeypox virus; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 197128.79

構造登録者

Xu, Y.,Wu, Y.,Zhang, Y.,Fan, R.,Yang, Y.,Li, D.,Yang, B.,Zhang, Z.,Dong, C. (登録日: 2022-11-07, 公開日: 2023-11-15, 最終更新日: 2025-07-02)

• 主引用文献: Xu, Y.,Wu, Y.,Zhang, Y.,Fan, R.,Yang, Y.,Li, D.,Zhu, S.,Yang, B.,Zhang, Z.,Dong, C.; Cryo-EM structures of human monkeypox viral replication complexes with and without DNA duplex.; Cell Res., 33:479-482, 2023; PubMed: 36973539; DOI: 10.1038/s41422-023-00796-1

実験手法

ELECTRON MICROSCOPY (3.05 Å)